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Monitoring Post-Lung Transplant Recipients

Correlation, 18 Months Post-Left Lung Transplant - 56 y.o. Female
Background:
The image by the VRIxp™ and the Posterior Perfusion Scan were performed 18 Months post-left lung transplant, as part of a correlation study.  The purpose of the study was to assess regional lung function in single lung transplant recipients, by comparing the regional Q-signals with the regional quantitative lung (QLD) data produced by the VRIxp™ device.
 

                                



                      




VQ Scan:  
23% Right Lung 
77% for the Left Lung

1 Month Post-Double Lung Transplant - 53 y.o. Female
One Month Post-transplant Baseline:

 
                                 
       

Baseline Image of the VRIxp™ device:
 
 Abnormal right lung reflecting lower vibration 
  intensity 
 Expiratory phase (frames 23- 24, 49-50) 
 Amputation of the left lower  lung.  

 
 
 1 Month Follow-up:


                                  

Image by the VRIxp™ device:

  Lower vibration intensity and an even smaller 
    vibration energy area
  The left lower lung is still  amputated in the expiratory 
   phase (frames 14-15, 36-37). 

 

Explanation:  both images by the VRIxp™ device demonstrates a clear difference between the right and left lungs.  The fact that in the expiratory phase the right lung has higher vibration intensity than the left, raise the suspicion that the higher vibration intensity that we see on the left is not related to actual ventilation but rather generated by another vibration source within the lung causing the lung to look hyper-inflated.  Futhermore, the familiar miniscus shape of the lower left lung in the expiratory phase reconfirm the presence of pleural effusion in the immediate source.

1 Month Post-Double Lung Transplant - 40 y.o. Female 
Baseline:

 
                                
 
Normal chest X-Ray

Image by the VRIxp™ sytem:
  Abnormal pattern in the vibration energy graph  
  High amplitude of the inspiratory phase
  No energy in the expiratory phase dynamic 
  Disturbance in the vibration energy pattern 
  Inconsistent progress
  Uneven distribution of vibration energy in both 
    lungs
  Diffused crackles are  evident on both lung fields
    
PFT:  FEV1 50%

 1 Month Follow-up:                             

 
                                   

Normal chest X-Ray

Image by the VRIxp™ sytem:

  Inconsistent progression  (inverse dominance frames 
   13-17)
  Improved distribution of  vibration energy
  No crackles are evident 
PFT:  FEV1 49%. 

Explanation: The improvement of the patient correlates with theclinical  improvement of the patient. Other objetive measures such as pulmonary function tests (PFT) and chest X-Ray did not show any clinical improvement.