Deep Breeze - Lung Transplant

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Monitoring Post-Lung Transplant Recipients

Correlation, 18 Months Post-Left Lung Transplant - 56 y.o. Female
Background: The image bythe VRIxp™ and the Posterior Perfusion Scan were performed 18 Months post-left lungtransplant, as part of a correlation study.The purpose of the study was to assess regional lung function in single lung transplant recipients, by comparingthe regional Q-signals with the regional quantitative lung (QLD) data produced by the VRIxp™ device.
		VQ Scan: 23% Right Lung 77% for the Left Lung

1 Month Post-Double Lung Transplant - 53 y.o. Female

One Month Post-transplant Baseline:

Baseline Image of the VRIxp™ device:

Abnormal right lung reflecting lower vibration
intensity
Expiratory phase(frames 23- 24, 49-50) Amputation of the left lower lung.

1 Month Follow-up:

Image by the VRIxp™ device:

Lower vibration intensityand an even smaller
vibration energy area

The left lower lung is still amputatedin the expiratory
phase (frames 14-15, 36-37).

Explanation:both images by the VRIxp™ device demonstrates a clear difference between the right and left lungs.The fact that in the expiratoryphase the right lung has higher vibration intensity than the left,raise the suspicion that the highervibration intensity that we see on the left is not related to actual ventilation but rathergenerated by anothervibration source within the lung causing the lung to look hyper-inflated. Futhermore,the familiar miniscus shape of the lower left lung in the expiratory phase reconfirm the presence of pleural effusion in the immediate source.

1 Month Post-Double Lung Transplant - 40 y.o. Female

Baseline:

_{^{Normal chest X-Ray

Image by the VRIxp™ sytem:

Abnormal pattern in the vibration energy graph High amplitude of theinspiratory phase

No energy in the expiratory phase dynamic

Disturbance in the vibration energy pattern

Inconsistent progress

Uneven distribution of vibration energy in both

    lungs

Diffused crackles are evident on both lung fields



PFT:  FEV₁ 50%}}

1 Month Follow-up:

Normal chest X-Ray

Image by the VRIxp™ sytem:

Inconsistent progression (inverse dominance frames
13-17)

Improved distribution of vibration energy

No crackles are evident
PFT: FEV₁ 49%.

Explanation:The improvement of the patient correlates with theclinical improvement of the patient.Other objetive measures such as pulmonary function tests (PFT) and chest X-Ray did not show any clinical improvement.