| Case 1: COPD Emphysema - 70 y.o. Male |
The VRIxp™ image displays clear abnormalities throughout the breathing cycle:
 Uneven distribution of vibration energy
Difficult to delineate inspiration from exspiration
Vibration energy bar indicates a low vibration
energy
Inconsistent progression and regression
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Case 2: COPD Emphysema Therapy, Significant Improvement - 70 y.o. Male |
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Image by the VRIxp™ Device Pre-Treatment:
Moderate dynamic disturbance and the
Lower part of both lungs has diminished intensity
PFT results:
FEV1 76%
Image by the VRIxp™ Device Post-Treatment:
Mild dynamic disturbance
Improved distribution of the vibration energy in the lower parts of both lungs PFT results:
FEV1 82%
Note: the improvement of the post-treatment image is more dramatic than that of the PFT’s.
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Case 3: COPD Emphysema Therapy, Insignificant Improvement - 60 y.o. Male |
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Image by the VRIXP™ device pre-beta agonist treatment:
Inconsistant dynamic progression of the lungs in especially the left lung that lags behind the right lung
Left lung displays diminshed vibration intensity and is considerably smaller than right lung
The left lung on the image by the VRIXP™ device post-treatment:
Slight improvement with increased vibration intensity.
Similar charactaristics of the pre-treatment image.
Explanation: dramatic improvement is not expected in COPD patients pre and post-treatment.
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Case 4: Comparison to Existing Modalities - Emphysema 60 y.o Male |
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Image by the VRIxp™ device - Right Lung:
Severe dynamic disturbance
Smaller in size and in vibration intensity
During expiration and the lower part shows an area of hyper intensity
Consistent with the Chest-X-Ray & CT - Left Lung:
Diminished intensity
Explanation: The severe dynamic disturbance of vibration energy in particularly the right during inspiration is an indication in the limitation of airflow to this lung, the area of dimunition in vibration intensity in the upper right lung during expiration can be accounted to the decreased function the lung.
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Case 5: Monitoring Hospitalized COPD, Emphysema - 77 y.o. Male |
Patient History:
This patient admitted and treated for COPD Emphysema, was subsequently monitored for the duration of his stay by various methods including pulmonary function tests (PFT) and standard 12 second non-invasive repetitive procedures by the VRIxp™ device was performed. The VRI™ technology offers an exciting new, quick and a cost-effective method to repeatedly monitor lung condition in hospitalized COPD patients at the bedside.
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Admission:
Image by the VRIxp™ Device:
Severe dynamic disturbance in vibration
energy pattern
Inconsistent progression with inverse dominance
Uneven distribution of the vibration energy
Wheezes (red dots) are indicated in the right lung
QLD shows an abnormal contribution
Patient-work up and physical examination:
Patient experienced dyspnea, cough with yellow
sputum
Pulmonary function tests:
FEV1 35%, PaO2 mmHg 55, PaCO2 mmHg 44.1
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Follow-up 4 Days Post-Admittance:
Image by the VRIxp™ Device:
The vibration energy still demonstrates
inconsistent progression with inverse dominance
Wheezes (red dots) are not indicated
QLD shows an abnormal contribution
Patient-work up and physical examination:
Patient's dyspnea has improved.
Pulmonary function tests:
FEV1 36.1%, PaO2 mmHg 62, PaCO2 mmHg 40.8
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Follow-up 6 Days Post-Admittance:
Image by the VRIxp™ Device:
The vibration energy pattern demonstrates an
improvement when compared to previous images
There is still a mild dynamic disturbance, the lungs
are more synchronized with no inverse dominance
Wheezes are not indicated
QLD shows a near normal contribution
Patient-work up and physical examination:
Patient had improved exercise capacity
Pulmonary function tests:
FEV1 38%, PaO2 mmHg 69, PaCO2 mmHg 38.8
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Follow-up 10 Days Post-Admittance:
Image by the VRIxp™ Device:
Once again the vibration energy pattern shows
improvement with almost no dynamic disturbance
and a more consistent progression throughout the
respiratory cycle
There is still however and uneven distribution of
vibration energy, as expected in the majority of
COPD patients
QLD shows a near normal contribution
Patient-work up and physical examination:
Patient had no sputum or any cough
Pulmonary function tests:
FEV1 38.8%, PaO2 mmHg 69.5, PaCO2 mmHg 39.5
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Discharge:
Image by the VRIxp™ Device:
On discharge the vibration energy pattern shows
a near normal pattern, however it still has a
prolonged expiratory phase
The lungs are more synchronized, and the
distribution of vibration energy has improved
QLD shows a normal contribution
Patient-work up and physical examination:
Patient's overall clinical condition has improved
Pulmonary function tests:
FEV1 38.5%, PaO2 mmHg 69.6, PaCO2 mmHg 39.5 |
| Explanation: For the duration of the patient's hospitalization the image by the VRIXP™ device has improved correlating directly with patient's clinical improvement, contratry to other objective measurements. As to be expected the image is still abnormal. |